42. The San Francisco 49ers have a ton of work to do before they can be back on the road to contention in the NFC West. One of their underlying problems is the steady deterioration of their offensive line, especially along the interior. A guard going #2 overall is almost unheard of, but there are rare exceptions. Quenton Nelson is one of them. Almost every credible scout believes the Notre Dame guard will be All-Pro when he gets to the NFL. There just aren’t any holes in his game. He’s big, strong, physical, nasty and fundamentally sound. Plug him in and let him eat.. OG. Notre Dame. Quenton Nelson . 2. player